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  • Mendelian Randomization : Methods for Causal Inference Using Genetic Variants
    Mendelian Randomization : Methods for Causal Inference Using Genetic Variants

    Mendelian Randomization: Methods For Causal Inference Using Genetic Variants provides thorough coverage of the methods and practical elements of Mendelian randomization analysis.It brings together diverse aspects of Mendelian randomization from the fields of epidemiology, statistics, genetics, and bioinformatics. Through multiple examples, the first part of the book introduces the reader to the concept of Mendelian randomization, showing how to perform simple Mendelian randomization investigations and interpret the results.The second part of the book addresses specific methodological issues relevant to the practice of Mendelian randomization, including robust methods, weak instruments, multivariable methods, and power calculations.The authors present the theoretical aspects of these issues in an easy-to-understand way by using non-technical language.The last part of the book examines the potential for Mendelian randomization in the future, exploring both methodological and applied developments. FeaturesOffers first-hand, in-depth guidance on Mendelian randomization from leaders in the fieldMakes the diverse aspects of Mendelian randomization understandable to newcomersIllustrates technical details using data from applied analysesDiscusses possible future directions for research involving Mendelian randomizationSoftware code is provided in the relevant chapters and is also available at the supplementary websiteThis book gives epidemiologists, statisticians, geneticists, and bioinformaticians the foundation to understand how to use genetic variants as instrumental variables in observational data. New in Second Edition: The second edition of the book has been substantially re-written to reduce the amount of technical content, and emphasize practical consequences of theoretical issues.Extensive material on the use of two-sample Mendelian randomization and publicly-available summarized data has been added.The book now includes several real-world examples that show how Mendelian randomization can be used to address questions of disease aetiology, target validation, and drug development

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  • How we Get Mendel Wrong, and Why it Matters : Challenging the narrative of Mendelian genetics
    How we Get Mendel Wrong, and Why it Matters : Challenging the narrative of Mendelian genetics

    This book illustrates that the stereotypical representations of Gregor Mendel and his work misrepresent his findings and their historical context.The author sets the historical record straight and provides scientists with a reference guide to the respective scholarship in the early history of genetics.The overarching argument is twofold: on the one hand, that we had better avoid naïve hero-worshipping and understand each historical figure, Mendel in particular, by placing them in the actual sociocultural context in which they lived and worked; on the other hand, that we had better refrain from teaching in schools the naive Mendelian genetics that provided the presumed “scientific” basis for eugenics. Key FeaturesCorrects the distorting stereotypical representations of Mendelian genetics and provides an authentic picture of how science is done, focusing on Gregor Mendel and his actual contributions to scienceExplains how the oversimplifications of Mendelian genetics were exploited by ideologues to provide the presumed “scientific” basis for eugenicsProposes a shift in school education from teaching how the science of genetics is done using model systems to teaching the complexities of development through which heredity is materialized

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  • High-Performance Nutrition for Masters Athletes
    High-Performance Nutrition for Masters Athletes

    It’s an undisputed fact that the body’s physiological needs change as you age.But that doesn’t mean you can’t continue to compete and perform at your best.In High-Performance Nutrition for Masters Athletes, you’ll find practical advice for fueling your active lifestyle—now and for decades to come. The key to effectively adapting your nutrition plans is first understanding how needs change over time and how expected results shift through the decades.Explore the science behind proper fueling for training and competition with the current guidelines for carbohydrate, protein, and fat intake plus advice on proper hydration, avoiding the dangers of underfueling, and nutrition for optimal recovery. High-Performance Nutrition for Masters Athletes will then take you inside the fueling strategies for precompetition, competition, and recovery: Gain an understanding of the need for different types or amounts of nutrients at different times and get easy-to-follow guidance on how to meet those needs. Learn how to energize with carbohydrate, build muscle with protein, and meet your hydration needs for optimal athletic performance. Know the role vitamins, minerals, and supplements can play in a nutrition plan and how devastating underfueling can be to athletic performance. Understand how chronic conditions such as high blood pressure, diabetes, and cardiovascular disease affect nutritional needs. Use the sample meal plans to help customize meals and snacks and reset eating habits to meet the needs of training and competition. Plus, throughout the book you will find accounts of amazing individuals—both well-known elite athletes and Olympians and everyday athletes—who have adapted their nutrition and training regimes to stay at the top of their game year in and year out. Comprehensive yet practical, High-Performance Nutrition for Masters Athletes provides the latest research, guidance, and strategies that you need to train harder, perform stronger, and recover faster.Fuel smart, and never let age slow you down. Earn continuing education credits/units! A continuing education exam that uses this book is also available.It may be purchased separately or as part of a package that includes both the book and exam.

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  • Womens Ballet Dance Gymnastics Leotards Figure Skating Acrobatics Performance Costume Long Sleeve
    Womens Ballet Dance Gymnastics Leotards Figure Skating Acrobatics Performance Costume Long Sleeve

    Womens Ballet Dance Gymnastics Leotards Figure Skating Acrobatics Performance Costume Long Sleeve

    Price: 9.39 € | Shipping*: 0 €
  • What is Mendelian genetics?

    Mendelian genetics is a set of principles established by Gregor Mendel in the 19th century that describes the inheritance of traits from parents to offspring. These principles include the concepts of dominant and recessive alleles, segregation, and independent assortment. Mendelian genetics forms the foundation of modern genetics and helps explain how traits are passed down through generations in a predictable manner.

  • Which Mendelian rule fits?

    The Mendelian rule that fits is the principle of segregation. This rule states that during the formation of gametes, the two alleles for a gene segregate from each other so that each gamete carries only one allele for each gene. This means that offspring receive one allele from each parent, and the combination of alleles determines the genetic traits of the offspring. This principle helps explain the inheritance patterns of single gene traits in offspring.

  • What do gymnasts or track and field athletes wear under their competition outfits?

    Gymnasts and track and field athletes typically wear compression shorts or briefs under their competition outfits. These undergarments provide support and coverage while allowing for freedom of movement. They also help to prevent chafing and offer a layer of protection during high-impact movements. Additionally, some athletes may choose to wear specialized performance underwear designed to wick away moisture and provide additional support.

  • What are the Mendelian inheritance rules?

    The Mendelian inheritance rules are a set of principles that describe how genetic traits are passed from parents to offspring. These rules include the principles of dominance, segregation, and independent assortment. Dominance refers to the fact that one allele of a gene may mask the expression of another allele. Segregation describes how alleles separate and are randomly distributed into gametes during meiosis. Independent assortment states that alleles of different genes are inherited independently of each other. These rules form the basis of classical genetics and are fundamental to understanding inheritance patterns in organisms.

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  • Womens Ballet Dance Gymnastics Leotards Figure Skating Acrobatics Performance Costume Long Sleeve
    Womens Ballet Dance Gymnastics Leotards Figure Skating Acrobatics Performance Costume Long Sleeve

    Womens Ballet Dance Gymnastics Leotards Figure Skating Acrobatics Performance Costume Long Sleeve

    Price: 9.39 £ | Shipping*: 0 £
  • Talent to Triumph : How Athletes Turn Potential into High Performance
    Talent to Triumph : How Athletes Turn Potential into High Performance

    Talented athletes across all sports don't always go on to fulfil their true potential. The ratio of those that do, compared to those that don't is incredibly small. You mightn't have found the right sport for you, you might have faced setbacks, barriers, bad luck or lack of facilities.You mightn't have the knowledge required to optimise your performance, look after your wellbeing or take a long-term approach to your sporting journey. This book is the answer. Olympic Champion, Amy Williams MBE guides you through your entire sporting journey, using her own experiences & those of some of Britain's greatest athletes to help you turn your talent into your triumph. You'll learn about mindset, confidence, teamwork, overcoming barriers & setbacks, dealing with injuries, longevity, training & preparation, talent identification schemes, maximising competition/match day outcomes & much more besides. Featuring original insight from elite performers across many sports & other relevant fields, including Rebecca Adlington (Swimming), Vassos Alexander (Sports Broadcaster), Brian Ashton (rugby), Graham Bell (Skiing), Freddie Burns (Rugby), Maria Costello (Motorcycling), Laura Deas (Skeleton), Heather Fell (Modern Pentathlon), Jason Fox (Broadcaster, former UK Special Forces Soldier), Jason Gardener (Sprints), Helen Glover (Rowing), Sally Gunnell (400m Hurdles), Danny Holdcroft (Head of Performance), Colin Jackson (110m Hurdles), Jade Jones (Taekwondo), Katy Livingston (Modern Pentathlon), Chris Price (Head of Performance, English Institute of Sport), Susie Rodgers (Swimming), Vanessa Ruck (Motorcycling), Ellie Simmonds (Swimming), Heather Stanning (Rowing), Dame Sarah Storey (Cycling, Swimming), Lucy Stone (Breathing Techniques), Tanya Streeter (Freediving), Hannah White (Solo Sailing) & Professor Greg Whyte (Sport Psychologist & Pentathlete). Talent to Triumph is your full guide to maximising your sporting talent, whatever it may be.

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  • Practical Fueling for Endurance Athletes : Your Nutrition Guide for Optimal Performance
    Practical Fueling for Endurance Athletes : Your Nutrition Guide for Optimal Performance

    Endurance requires more than physical training. You need to fuel your body to optimize your training and be at your best on event day.Practical Fueling for Endurance Athletes delivers the practical, science-based information and strategies you need for long-term health and superior performance in your sport. Kylee Van Horn—registered dietitian, endurance athlete, and coach—will help you navigate the challenges of endurance sports with the following: Essential nutrition concepts that aren’t directed at weight loss The smart use of supplements Strategies for developing your ideal personal nutrition plan Unique nutrient needs of female athletes, including during pregnancy and menopause Plant-based fueling Special dietary needs Planning meals and snacks You’ll learn to design, test, and implement sport-specific nutrient intake for before, during, and after your workout or event to ensure your body has the right amount of energy at the right time. Throughout, you will find checklists, charts, and 28 easy-to-make recipes to help you take in adequate and appropriate nutrients for your unique needs.Get inspiration from the stories and strategies shared by endurance athletes such as Camille Herron, Sage Canaday, Nicole Mericle, and many others, showcasing how their nutrition plans fueled their success. No matter what endurance sport you train for—running, cycling, swimming, skiing, rowing, obstacle course racing, or something else—Practical Fueling for Endurance Athletes will equip you to reach your next personal best!

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  • Sport Retirement : The Experiences of Elite Female Gymnasts
    Sport Retirement : The Experiences of Elite Female Gymnasts


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  • What are the Mendelian laws in genetics?

    The Mendelian laws in genetics refer to the principles of inheritance discovered by Gregor Mendel in the 19th century. These laws include the law of segregation, which states that each individual has two alleles for a trait, and these alleles separate during the formation of gametes. The law of independent assortment states that the inheritance of one trait is not dependent on the inheritance of another trait. Finally, the law of dominance states that one allele can be dominant over another, determining the phenotype of the organism. These laws laid the foundation for our understanding of genetic inheritance.

  • What does the fourth Mendelian rule state?

    The fourth Mendelian rule, also known as the law of independent assortment, states that the inheritance of one trait is independent of the inheritance of another trait. This means that the alleles for different genes are passed on to offspring independently of one another, and the assortment of one pair of alleles does not influence the assortment of another pair of alleles. This rule helps explain the variety of genetic combinations that can occur in offspring, contributing to genetic diversity within a population.

  • What does the 5th Mendelian rule state?

    The 5th Mendelian rule states that genes located on different chromosomes assort independently during meiosis. This means that the inheritance of one gene does not affect the inheritance of another gene located on a different chromosome. This principle is known as Mendel's Law of Independent Assortment and helps explain the genetic diversity observed in offspring.

  • How does the 3rd Mendelian rule work?

    The third Mendelian rule, also known as the Law of Independent Assortment, states that different genes for different traits are inherited independently of each other. This means that the inheritance of one gene does not affect the inheritance of another gene. During meiosis, homologous chromosomes randomly assort and separate into different gametes, leading to the independent inheritance of different traits. This rule helps explain the genetic variability seen in offspring and the inheritance patterns of multiple traits.

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